PRE-OP18 March 2026

Colonoscopy - Merged + Timeline

Preparation Timeline

7 Days Before

O Stop these supplements (if applicable)

  • Iron supplements — Darkens stool and coats colon wall, hiding polyps
  • Fiber supplements (Metamucil, Benefiber, Citrucel) — Creates residue that is hard to clear
  • Fish oil, Vitamin E — Creates residue that is hard to clear
  • Ozempic, Mounjaro, Trulicity (weekly GLP-1s) — Slows gastric emptying → aspiration risk under

O Stop Weekly GLP-1 Medications

O Buy your supplies

[ ] Your prescribed bowel prep solution

[ ] Gatorade — yellow, green, or clear only (no red/purple/ orange)

[ ] Clear broth (chicken, beef, or vegetable)

  • Jell-O, apple juice, hard candy (no red/purple)
  • Straw (helps with drinking prep)
  • Baby wipes or flushable wipes
  • Vaseline or AtD ointment
  • Lemon wedges (optional — cuts prep taste)

5 Days Before

[ ] Stop Blood Thinners (With Doctor Approval)

  • Aspirin 81 mg - Continue
    Safe for all colonoscopies
  • Warfarin (Coumadin) - Stop 5 days before
    INR check; may need bridging therapy
  • Eliquis (apixaban) - Stop 48 hours before
    No bridging needed
  • Xarelto (rivaroxaban) — Stop 48 hours before
    No bridging needed
  • Pradaxa (dabigatran) - Stop 48-72 hours 72h
    if reduced kidney function
  • Plavix (clopidogrel) - Stop 5-7 days before
    Do NOT stop if recent stent
  • Effient (prasugrel) - Stop 7 days before
    Consult cardiologist
  • Brilinta (ticagrelor) — Stop 5 days before
    Consult cardiologist
Do not stop blood thinners on your own

Your prescribing doctor must approve the hold plan. Coordinate at least 2 weeks in advance.


3 Days Before

[ ] Start Low-Residue Diet

Eat soft, low-fiber foods. Avoid anything that leaves residue in your colon.

  • White bread, white rice, pasta
  • Eggs (any style)
  • Chicken, fish, turkey, tofu
  • Bananas, applesauce, canned fruit
  • Well-cooked carrots, green beans
  • Peeled potatoes
  • Smooth peanut butter, yogurt
  • Nuts, seeds, popcorn
  • Raw vegetables, salads, corn
  • Beans, lentils
  • Berries, dried fruit
  • Whole wheat, brown rice, oatmeal
  • Tough/fatty meat, bacon
  • Granola, high-fiber cereal

[ ] Stop these NSAIDs + SGLT2 Inhibitors

  • Ibuprofen (Advil), Naproxen (Aleve) — Increases bleeding risk. Tylenol is OK.
  • Jardiance, Farxiga, Invokana (SGLT2 inhibitors) — Risk of euglycemic DKA during fasting + dehydration
  • Victoza, Adlyxin (daily GLP-1s) — Slows gastric emptying — hold 1 day before

1 day before

[ ] Start Clear Liquids Only Diet - No Solid Food

If you can see through it, you can probably have it.

  • Water (unlimited)
  • Apple juice, white grape juice Gatorade - yellow/green/clear Clear broth
  • Black coffee or tea (no milk)
  • Jell-O (yellow/green)
  • Sprite, ginger ale
  • Hard candy, honey
  • Red, purple, or blue colored liquids
  • Milk
  • Cream
  • Orange juice, juice with pulp
  • Smoothies
  • Alcohol
  • Soup with chunks

[ ] Hold or Reduce Diabetes Medications

Start 5–6 hours before your arrival time. Finish at least 2 hours before.

Request an early morning procedure

to minimize fasting time. Use sugar-containing clear liquids
(regular Gatorade) to keep blood sugar up

  • Metformin — Hold starting day before. Lactic acidosis risk with dehydration.
  • Glipizide / Glyburide — Hold day before + day of. High hypoglycemia risk while fasting.
  • Long-acting insulin (Lantus, Levemir, Tresiba) — Take 50% of usual dose night before and morning of.
  • Mealtime insulin (Humalog, NovoLog) —- Skip entirely while fasting.
  • DPP-4 inhibitors (Januvia, Tradjenta) — Generally safe to continue

[ ] Start your Prep Solution

Two doses — one the evening before, one early morning of. Check instructions below to see how.

Before you start

Apply Vaseline around your anal area now. Use baby wipes instead of toilet paper. Drink prep cold through a straw.

Prep Solutions Instructions

See full instructions for your specific prep solution:

Evening Dose - 5:00-6:00 P.M

  • Pour one 6-oz bottle into mixing container. Add water to the 16-oz line.
  • Drink all 16 oz.
  • Then drink two additional 16-oz glasses of water over the next hour.

Morning Dose - 5-6 hours before arrival

  • Repeat with second 6-oz bottle. Mix to 16 oz, drink, then two more 16-oz waters
  • Finish at least 2 hours before your procedure

Evening Dose

  • Mix entire 238g MiraLAX bottle into 64 oz Gatorade. Should already be cold.
  • 5:00 PM: Take 4 Dulcolax tablets with water.
  • 6:00 PM: Drink 32 oz (half) — 8 oz glass every 10–15 min.
  • Bowel movements begin in 30–60 minutes.

Morning Dose - 5-6 hours before arrival

  • Drink remaining 32 oz — 8 oz every 10–15 min.
  • Finish at least 2 hours before your procedure.

Evening Dose

  • 5:00 PM: Drink one entire 5.4-oz bottle.
  • Then drink at least 40 oz of clear liquids over the next 5 hour

Morning Dose - 5-6 hours before arrival

  • Drink the second 5.4-oz bottle.
  • Follow with at least 24 oz of clear liquids within 1 hour.
  • Finish at least 2 hours before your procedure.

Evening Dose

  • Fill jug with lukewarm water to the fill line. Shake. Should already be cold.
  • 6:00 PM: Drink 2 liters (half) — 8 oz every 10–15 min over ~90 min.

Morning Dose - 5-6 hours before arrival

  • Drink remaining 2 liters — 8 oz every 10–15 min.
  • Finish at least 2 hours before your procedure.

Evening Dose - 5:00- 6:00 P.M

  • Open Bottle 1 (12 tablets). Remove and discard the desiccant packet.
  • Fill container with 16 oz water. Swallow one tablet every 1–2 min with sips.
  • Then drink two more 16-oz containers of water, 30 min each.

Morning Dose - 5-6 hours before arrival

  • Open Bottle 2. Discard desiccant.
  • Same process: one tablet every 1–2 min, then three 16-oz waters.

Comfort Tips for Prep Night

  • Chill it — Cold prep tastes much better. Refrigerate 2+ hours.
  • Use a straw — Placed toward back of mouth — bypasses most taste buds.
  • Suck on lemon — Between glasses. Hard candy works too.
  • Nauseous? — Slow pace to every 20 min. Take a 30-min break. Ask doctor about Zofran.

Can't finish?

Drink as much as you can. Don't cancel — call your doctor. Partial compliance is better than none.

What to expect on surgery day

Navigate your procedure with confidence by understanding what happens before, during, and after you arrive at the facility.

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